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  • Autism

    Autism is a mental condition, present from early childhood, characterized by great difficulty in communicating and forming relationships with other people and in using language and abstract concepts.

    What is Autism


    Autism is a disorder of neural development and affects approximately 1 out of every 150 children born is diagnosed with autism that appears in the first 3 years of life mainly charterized by impaired social interaction and communication and by restricted and repetitive behavior. Autism affects information processing in the brain by altering how nerve cells & their synapses connect and organize. There is no fix reason for autism but it may occur due to environmental, immunological and neurological factors.

    Conditions of Autism


    Autism diagnosed children suffer from two major conditions

    1. Hypo-perfusion (Decreased blood flow to brain)
    2. Immune dysregulation (Immune inflammation)

    1. Hypo- perfusion: Hypo perfusion may contribute to functional defects not only by inducing hypoxia (an oxygen deficit that prevents normal brain function) but also by allowing for abnormal metabolite or neurotransmitter accumulation which affect neuron development. That's why brain does not function normally.

    2. Immune dysregulation (Immune inflammation): Autistic children often have continually suppressed immune systems and chronic inflammation (brain becomes inflamed). Immune dysregulation is very apparent in gastrointestinal system. Brain inflammation also create problem for neuron formation.

    Don't worry. We are here to help you to recover soon.

    Introduction:


    Currently the treatment for autism can be divided into behavioral, nutritional and medical approaches but they don't have any major benefits. Stem cells in the combination of current treatment can increase improvement for autism patient. We have our very specific stem cell treatment protocol for autism patient. Treatment with autologous bone marrow derived Mesenchymal stem cells (MSCs) provide multiple mechanisms including neuroprotection, immunomodulation and neuroregeneration in autism patients after intrathecally/intravenously transplantation.

    We use bone marrow stem cell concentrate which contain all types of regenerative cells as following Mesenchymal stem cells (CD44+), Endothelial Stem Cells (CD31+), Hematopoietic stem cells (CD34+) that are useful for autism treatment. Hematopoietic stem cells (CD34+) which is the source of endothelial stem cells has very crucial role in the treatment of autism because when bone marrow derived CD34+ cells it induce the new blood vessels from preexisting arteries and we transplant improve blood flow to the brain. Mesenchymal stem cells (CD44+) has very important role to suppress inflammation in children with autism through secretion of anti-inflammatory cytokines such as IL-10, TGF-beta and IL-1.


    Autism Rehabilitation:-


    Rehabilitation is the part of stem cell therapy. CP patients should have some kind of rehabilitation to help maximize their potential and to help teach techniques which make everyday life easier. Rehabilitation including physiotherapy provides enhanced environment to make stem cell more functional by helping the cell migrating and proliferation fast.

    Key Points:-

    1. Physical therapy may improve your ability to perform daily activities and make you feel better.
    2. Occupational therapy may help you perform daily activities more easily-especially those involving your hands and arms, such as grooming, dressing, and eating. Assistive devices may be used to help you perform daily tasks.
    3. Speech therapy may improve your communication skills if cerebral palsy symptoms are making speaking difficult.
    4. Cognitive retraining may help improve cognitive impairment caused by cerebral palsy

    Autism is a mental condition, present from early childhood, characterized by great difficulty in communicating and forming relationships with other people and in using language and abstract concepts.

    Scientific Papers


    1. Ichim et al. 2007, Journal of Translational Medicine. Stem cell Therapy for Autism.
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