Currently, RA is treated with immune suppressive agents such as steroids, methothrexate, cyclosporine, gold, and more recently infliximab (Remicade). Despite inducing temporary improvement, these approaches possess long-term adverse effects due to non-specific inhibition of immune responses.
Stem cell therapy induces healing activity with various forms of arthritis. Besides healing activity of damaged tissues in RA related patients, stem cells provide immunomodulation (to shut off pathological responses) and also start producing anti-inflammatory cytokines (especially Mesenchymal stem cells) to stop the immune attack on synovial fluid of joints.
Physical therapy is one of the parts of stem cell therapy because physical therapy stimulates muscles, bones, and joints through exercise or other methods. The result is more strength, tone, and overall fitness.