Stem Cell Therapy for Diabetic Retinopathy


Retinopathy is any damage to the retina of the eyes, which may cause vision impairment. Retinopathy often refers to the retinal vascular disease or damage to the retina caused by abnormal blood flow. The condition can develop in anyone who has type 1 or types 2 diabetes. The longer you have diabetes and the less controlled your blood sugar is, the more likely you are to develop this eye complication. Age-related macular degeneration is technically included under the umbrella term retinopathy but is often discussed as a separate entity. Retinopathy, or retinal vascular disease, can be broadly categorized into proliferative and non-proliferative types. Frequently, retinopathy is an ocular manifestation of systemic disease as seen in diabetes or hypertension. Diabetic retinopathy is the leading cause of blindness in working-aged people. It accounts for about 5% of blindness worldwide and is designated a priority eye disease by the World Health Organization.

At first, Diabetic Retinopathy may cause no symptoms or only mild vision problems. Eventually, it can cause blindness. The list of diseases for which stem cell treatments have been shown to be beneficial is still very short. The best-defined and most extensively used stem cell treatment is hematopoietic (or blood) stem cell transplantation, for example, bone marrow transplantation, to treat certain blood and immune system disorders or to rebuild the blood system after treatments for some kinds of cancer. Some bone, skin and corneal (eye) injuries and diseases can be treated by grafting or implanting tissues, and the healing process relies on stem cells within this implanted tissue. These procedures are widely accepted as safe and effective by the medical community. When to see a doctor: Careful management of your diabetes is the best way to prevent vision loss. If you have diabetes, see your eye doctor for a yearly eye exam with dilation — even if your vision seems fine.


Pregnancy may worsen diabetic retinopathy, so if you’re pregnant, your eye doctor may recommend additional eye exams throughout your pregnancy. Contact your eye doctor right away if your vision changes suddenly or becomes blurry, spotty or hazy. Stem cell therapy in Delhi in the general designation, “stem cell” encompasses many distinct cell types. Commonly, the modifiers, “embryonic,” and “adult” are used to distinguish stem cells by the developmental stage of the animal from which they come, but these terms are becoming insufficient as new research has discovered how to turn fully differentiated adult cells back into embryonic stem cells and, conversely, adult stem cells, more correctly termed “somatic” stem cells meaning “from the body”, are found in the fetus, placenta, umbilical cord blood, and infants. Therefore, this review will sort stem cells into two categories based on their biologic properties – pluripotent stem cells and multipotent stem cells. Their sources, characteristics, differentiation, and therapeutic applications are discussed.

Stem Cell Therapy for Retinopathy in India promises of cures for human ailments by stem cells have been much touted but many obstacles must still be overcome through retinopathy treatment. First, more human multipotent cell research is needed since stem cell biology differs in mice and men. Second, the common feature of unlimited cell division shared by cancer cells and pluripotent stem cells must be better understood in order to avoid cancer formation. Third, the ability to acquire large numbers of the right cells at the right stage of differentiation must be mastered. Fourth, specific protocols must be developed to enhance the production, survival, and integration of transplanted cells. Finally, clinical trials must be completed to assure safety and efficacy of the stem cell therapy. When it comes to stem cells, knowing they exist is a long way from using them therapeutically.

Stem cell therapy may provide some good advantages in case of such eye related disease:-

• The stem cell has the property to regenerate retinal pigment epithelium cells, optic nerve, macular cells, and photoreceptor cells.

• Stop the further progression of this disease-

• So overall it may improve some vision.

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